Amytracker Mix&Try
Amytracker Mix&Try is our recommended option for starting out with using Amytracker. It contains 10 µL of each variant. Testing the variants will allow you to determine which Amytracker is best suited for your experiments and available instruments.
All Amytracker variants label Aβ plaques and neurofibrillary tangles in tissue sections with AD pathology and α-synuclein aggregates in tissue sections with PD pathology. The optotracers are exceptionally photostable and fluorogenic. The variants differ with regards to affinity, cellular uptake and excitation and emission wavelengths (see Table below). When bound to a target, Amytracker can be imaged using epifluorescence, confocal and superresolution microscopy. Spectral information can be acquired using a fluorescence spectrophotometer. Contact us to learn more about Amytracker applications.
Exmax | Emmax | Recommended filter-sets | |
---|---|---|---|
Amytracker 480 | 420 nm | 480 nm | DAPI |
Amytracker 520 | 460 nm | 520 nm | FITC, GFP |
Amytracker 540 | 480 nm | 540 nm | FITC, GFP, YFP |
Amytracker 630 | 520 nm | 630 nm | PI, Cy3, TxRed, mCherry, Cy3.5 |
Amytracker 680 | 530 nm | 680 nm | PI, mCherry, Cy3.5 |
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